Studies suggest people with a certain blood type may have a greater chance of reaching 100

Iron levels showed a similar pattern. Very low iron was linked to lower odds of living to 100. The lesson here is that extremes aren’t ideal. A steady, moderate range is what seems to matter most.

Kidney function was also significant. Those who lived the longest generally had healthier kidneys in midlife, allowing their bodies to process toxins, medications, and blood pressure for decades. Liver function was important too, but not as drastically. Inflammation was consistently reduced in centenarians and supercentenarians. Less inflammation may help keep organs and tissues resilient as the years tick by.

The Role of Genetics

Genes clearly play a part in longevity. Other studies reviewed alongside the Swedish research highlight variants in genes like FOXO3A, which regulates stress resistance and insulin signaling; APOE and PON1, which affect cardiovascular health and lipid metabolism; and TP53 and P21, which help control cell cycles and protect against age-related damage.

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